Author: Damian Soong
Multiple Manufacturers: NTI Drugs and Switching Between Generics
NTI drugs like levothyroxine and tacrolimus have a narrow margin between effective and toxic doses. Switching between generic manufacturers can affect blood levels and cause serious side effects-even when FDA-approved. Here's what you need to know.
Cumulative Drug Toxicity: How Side Effects Build Up Over Time
Cumulative drug toxicity is when medications build up in your body over time, causing side effects that appear only after months or years. Learn how it happens, who's at risk, and how to prevent it.
Long-Term Antihistamine Use: Why They Might Stop Working and What to Do
Many people feel their antihistamines stop working over time, but true tolerance is rare. Learn why symptoms return and what actually helps-higher doses, nasal sprays, or immunotherapy-not just switching pills.
Metformin Side Effects: How to Manage Gastrointestinal Issues and Understand Lactic Acidosis Risk
Metformin is the first-line treatment for type 2 diabetes, but gastrointestinal side effects are common and lactic acidosis is a rare but serious risk. Learn how to manage stomach issues, recognize warning signs, and stay safe while taking this essential medication.
Extended-Release vs. Immediate-Release Medications: When Timing Matters for Safety
Extended-release and immediate-release medications work differently-and mixing them up can be dangerous. Learn how timing affects safety, effectiveness, and risk of overdose.
Carpal Tunnel Syndrome: Understanding Wrist Pain and Nerve Decompression
Carpal tunnel syndrome causes wrist pain and numbness from nerve compression. Learn what really causes it, how to diagnose it, and which treatments work - from splints to surgery - based on the latest medical evidence.
Specialty Prescribing: Why Specialists Stick With Brand-Name Drugs
Specialists often choose brand-name specialty drugs over cheaper alternatives due to lack of clinical data, insurance barriers, and financial incentives from PBMs. Less than 7% of prescriptions drive over 70% of drug spending.
IBS Diet Guide: FODMAP, Low-Residue, and Elimination Plans Explained
Learn how the low-FODMAP, low-residue, and elimination diets work for IBS. See which one is most effective, how to do them right, and what to expect. Evidence-based, practical, and real-world tested.
Manufacturing Transparency: How to Access FDA Inspection Records for Quality Compliance
Understand how FDA inspection records work, what manufacturers must disclose, and how to prepare for inspections. Learn the rules on record retention, Form 483 responses, and the new push for remote audits.
Red Flag Drug Combinations to Avoid for Safer Treatment
Certain drug combinations can be deadly-even when taken as prescribed. Learn the most dangerous mixes like opioids with alcohol or benzodiazepines, and how to avoid life-threatening interactions.
