Category: Drug Information - Page 2

Diabetes Medication Interactions: Dangerous Drug Combinations to Avoid

Certain diabetes drug combinations can cause dangerous drops or spikes in blood sugar. Learn the top risky pairs, how to avoid them, and what safer options exist in 2025.

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Canagliflozin and Amputation Risk: What You Need to Know Now

Canagliflozin increases the risk of foot and leg amputations in certain people with diabetes. Learn who’s at risk, how to prevent complications, and how this drug compares to other SGLT2 inhibitors like Jardiance and Farxiga.

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Sulfonylureas and Hypoglycemia: Understanding Low Blood Sugar Risks and How to Prevent Them

Sulfonylureas are effective for type 2 diabetes but carry a high risk of dangerous low blood sugar. Learn which drugs are safest, how to prevent hypoglycemia, and what to ask your doctor if you're on one.

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Insomnia in Older Adults: Safer Medication Choices

Insomnia in older adults is common and risky. Learn which sleep medications are safest-like low-dose doxepin and ramelteon-and which to avoid, including benzodiazepines and z-drugs. Discover non-drug options and real-world patient experiences.

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Azathioprine and Allopurinol: How Low-Dose Combination Therapy Prevents Toxic Metabolite Buildup

LDAA therapy combines low-dose azathioprine with allopurinol to redirect toxic metabolite production, improving efficacy and reducing liver damage in IBD and autoimmune hepatitis patients with high TPMT activity.

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Patent Exclusivity vs Market Exclusivity: What’s the Real Difference in Drug Protection?

Patent exclusivity and market exclusivity are two separate legal tools that protect drugs from generics. One is about invention, the other about approval. Understanding the difference explains why some drugs stay expensive long after patents expire.

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H2 Blockers and Their Interactions with Antivirals and Antifungals

H2 blockers like famotidine and cimetidine can reduce the effectiveness of antivirals and antifungals by changing stomach acidity or interfering with liver enzymes. Know which drugs are affected and how to time doses safely.

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Nasal Antihistamine Sprays: Benefits, Side Effects, and How They Compare to Other Allergy Treatments

Nasal antihistamine sprays like Astepro offer fast relief for runny nose and sneezing with fewer drowsy side effects than oral meds. Learn how they work, their common side effects, and how they compare to steroid sprays and decongestants.

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Stability Testing Requirements: Temperature and Time Conditions for Pharmaceutical Products

Stability testing ensures pharmaceutical products remain safe and effective over time. Key requirements include specific temperature and humidity conditions defined by ICH Q1A(R2), with long-term, accelerated, and intermediate testing protocols for different drug types.

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Clozapine and Tobacco Smoke: How Smoking Affects Clozapine Levels and What to Do

Smoking can reduce clozapine levels by up to 50%, risking treatment failure or dangerous toxicity if not managed. Learn how CYP1A2 induction works, what doses to adjust, and why quitting smoking requires immediate medical attention.

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