Archive: 2025/11

Azathioprine and Allopurinol: How Low-Dose Combination Therapy Prevents Toxic Metabolite Buildup

LDAA therapy combines low-dose azathioprine with allopurinol to redirect toxic metabolite production, improving efficacy and reducing liver damage in IBD and autoimmune hepatitis patients with high TPMT activity.

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Patent Exclusivity vs Market Exclusivity: What’s the Real Difference in Drug Protection?

Patent exclusivity and market exclusivity are two separate legal tools that protect drugs from generics. One is about invention, the other about approval. Understanding the difference explains why some drugs stay expensive long after patents expire.

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Hearing Aid Batteries vs. Rechargeables: What Works Best for You

Discover the real pros and cons of disposable vs. rechargeable hearing aid batteries. Learn which option suits your lifestyle, budget, and hearing needs in 2025.

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H2 Blockers and Their Interactions with Antivirals and Antifungals

H2 blockers like famotidine and cimetidine can reduce the effectiveness of antivirals and antifungals by changing stomach acidity or interfering with liver enzymes. Know which drugs are affected and how to time doses safely.

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Physician Liability When Prescribing Generic Drugs: Legal Risks and How to Protect Yourself

Physician liability for prescribing generic drugs has surged since Supreme Court rulings shielded manufacturers from lawsuits. Learn how to protect yourself from legal claims by documenting counseling, knowing state laws, and using 'dispense as written' for high-risk medications.

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Nasal Antihistamine Sprays: Benefits, Side Effects, and How They Compare to Other Allergy Treatments

Nasal antihistamine sprays like Astepro offer fast relief for runny nose and sneezing with fewer drowsy side effects than oral meds. Learn how they work, their common side effects, and how they compare to steroid sprays and decongestants.

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Stability Testing Requirements: Temperature and Time Conditions for Pharmaceutical Products

Stability testing ensures pharmaceutical products remain safe and effective over time. Key requirements include specific temperature and humidity conditions defined by ICH Q1A(R2), with long-term, accelerated, and intermediate testing protocols for different drug types.

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Diabetic Retinopathy Screening Intervals and Treatment Options: What You Need to Know in 2025

Diabetic retinopathy is the leading cause of preventable vision loss in adults with diabetes. Learn the latest screening intervals based on risk, what treatments actually work, and how to protect your sight with personalized care.

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Clozapine and Tobacco Smoke: How Smoking Affects Clozapine Levels and What to Do

Smoking can reduce clozapine levels by up to 50%, risking treatment failure or dangerous toxicity if not managed. Learn how CYP1A2 induction works, what doses to adjust, and why quitting smoking requires immediate medical attention.

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Compare Emsam (Selegiline) with Alternatives for Depression Treatment

Emsam (selegiline) is a patch-based antidepressant for treatment-resistant depression. Learn how it compares to SSRIs, other MAOIs, bupropion, and esketamine - and which option might be right for you.

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