Tag: thiopurine metabolism

27 Nov
Azathioprine and Allopurinol: How Low-Dose Combination Therapy Prevents Toxic Metabolite Buildup

Azathioprine and Allopurinol: How Low-Dose Combination Therapy Prevents Toxic Metabolite Buildup

LDAA therapy combines low-dose azathioprine with allopurinol to redirect toxic metabolite production, improving efficacy and reducing liver damage in IBD and autoimmune hepatitis patients with high TPMT activity.

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